rs61427182
This variant is located in the XKR6 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
osteoarthritis
McDonald MN et al. “Novel genetic loci associated with osteoarthritis in multi-ancestry analyses in the Million Veteran Program and UK Biobank.” Nature Genetics 54(12):1816-1826 (2022)
Allele T
OR 0.99
p 2.0e-8
N 2,421,870
Major Consortium StudyLarge GWAS
European, South Asian, East Asian, African unspecified, Hispanic or Latin American
About XKR6
Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all XKR6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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