rs61758699

This variant is located in the ARHGAP21 gene.

▶

ClinVar annotation

Likely Benign★★★☆
3 submitters1 publication

not provided; Colorectal cancer; Ovarian serous cystadenocarcinoma; Thymoma; Thyroid cancer, nonmedullary, 1; Nonpapillary renal cell carcinoma

View on ClinVar →

About ARHGAP21

ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]

View all ARHGAP21 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…