rs619466
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
depressive symptom measurement
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele G
OR 0.01
p 3.0e-12
N 1,067,913
Large GWAS
European
neuroticism measurement
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele G
OR 0.02
p 3.0e-12
N 523,783
Large GWAS
European
Hill WD et al. “Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.” Molecular Psychiatry 25(11):3034-3052 (2020)
Allele G
OR 0.01
p 1.0e-8
N 270,059
Large GWAS
European
risk-taking behaviour
Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)
Allele A
OR 0.02
p 1.0e-10
N 404,291
Large GWAS
European
occupational attainment
Ko H et al. “Genome-wide association study of occupational attainment as a proxy for cognitive reserve.” Brain : a Journal of Neurology 145(4):1436-1448 (2022)
Allele A
OR 0.07
p 1.0e-8
N 248,847
Large GWAS
European
wellbeing measurement
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele G
OR 0.01
p 4.0e-12
N 410,603
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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