rs61995716
This variant is located in the SIGLEC15 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bronchial disease
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 3.96
p 2.0e-12
N 567,572
Major Consortium StudyLarge GWAS
multi-ancestry
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitterAbout SIGLEC15
Predicted to be involved in regulation of actin cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be located in membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SIGLEC15 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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