rs62477684

This is a downstream gene variant variant in the POM121C gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

obesity

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.04
p 4.0e-15
N 585,585
Major Consortium StudyLarge GWAS
multi-ancestry

About POM121C

Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Located in nuclear membrane and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all POM121C variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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