rs6457592
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
total blood protein measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.02
p 5.0e-21
N 394,642
Large GWAS
European
high density lipoprotein cholesterol measurement
Kim YJ et al. “The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.” Nature Communications 13(1):6642 (2022)
Allele C
OR 0.03
p 1.0e-15
N 288,127
Large GWAS
East Asian
hidradenitis suppurativa
Broadaway KA et al. “Genomic loci and molecular genetic mechanisms for hidradenitis suppurativa.” The British Journal of Dermatology 193(5):948-958 (2025)
Allele C
OR 1.19
p 5.0e-12
N 1,185,226
Large GWAS
multi-ancestry
BMI-adjusted hip circumference
Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)
Allele C
OR 0.02
p 2.0e-10
N 219,872
Major Consortium StudyLarge GWAS
European
anti-hepatitis B virus antibody measurement
Jeon S et al. “Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups.” Gigascience 13 (2024)
Allele T
OR 0.21
p 3.0e-8
N 1,785
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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