rs6545946
This is a upstream gene variant variant in the TMEM17 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Crohn's disease
Kenny EE et al. “A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.” Plos Genetics 8(3):e1002559 (2012)
Allele C
OR 1.16
p 7.0e-9
N 2,994
Large GWAS
European
About TMEM17
Involved in non-motile cilium assembly. Predicted to be located in ciliary membrane. Predicted to be part of MKS complex. Predicted to be active in ciliary transition zone. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM17 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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