rs6691427

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GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

BMI-adjusted hip circumference

Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)

Allele C

OR 0.03

p 6.0e-31

N 219,872

Major Consortium StudyLarge GWAS

European

BMI-adjusted waist-hip ratio

Allele C

OR 0.02

p 2.0e-11

N 219,872

Major Consortium StudyLarge GWAS

European

Pulit SL et al. “Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.” Human Molecular Genetics 28(1):166-174 (2019)

Allele C

OR 0.01

p 6.0e-9

N 379,501

Meta-analysisLarge GWAS

European

abdominal adipose tissue measurement

Agrawal S et al. “Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.” Nature Communications 13(1):3771 (2022)

Allele G

OR 0.07

p 5.0e-11

N 19,273

Large GWAS

European, East Asian, South Asian, African unspecified, NR

serum albumin amount

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele C

OR 0.01

p 5.0e-11

N 928,679

Large GWAS

multi-ancestry

high density lipoprotein cholesterol measurement

Allele C

OR 0.01

p 5.0e-9

N 928,679

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

rs6691427

GWAS Catalog Trait Associations (5)

BMI-adjusted hip circumference

BMI-adjusted waist-hip ratio

abdominal adipose tissue measurement

serum albumin amount

high density lipoprotein cholesterol measurement

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