rs669607

This is a upstream gene variant variant in the LINC01967 gene.

▶

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

multiple sclerosis

Sawcer S et al. “Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.” Nature 476(7359):214-9 (2011)

Allele C

OR 1.13

p 2.0e-15

N 26,621

Large GWAS

European

Sorosina M et al. “A multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility.” Journal of Neurology 269(8):4510-4522 (2022)

Allele C

OR 1.18

p 1.0e-10

N 4,046

Large GWAS

European

Epstein Barr virus nuclear antigen 1 IgG measurement, multiple sclerosis

Zhou Y et al. “Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.” Multiple Sclerosis (houndmills, Basingstoke, England) 22(13):1655-1664 (2016)

Allele A

OR —

p 4.0e-9

N 23,253

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…