rs6834314
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
aspartate aminotransferase measurement
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele A
OR 0.04
p 6.0e-108
N 928,679
Large GWAS
multi-ancestry
Chen VL et al. “Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.” Nature Communications 12(1):816 (2021)
Allele A
OR 16.00
p 2.0e-57
N 389,565
Large GWAS
multi-ancestry
serum alanine aminotransferase amount
Chen VL et al. “Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.” Nature Communications 12(1):816 (2021)
Allele A
OR 17.60
p 5.0e-69
N 390,812
Large GWAS
multi-ancestry
Chambers JC et al. “Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.” Nature Genetics 43(11):1131-8 (2011)
Allele A
OR 2.60
p 3.0e-9
N 61,089
Large GWAS
multi-ancestry
cirrhosis of liver
Emdin CA et al. “Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene-Environment Interaction Study.” Gastroenterology 160(5):1620-1633.e13 (2021)
Allele G
OR —
p 3.0e-54
N 440,073
Large GWAS
African unspecified, Asian unspecified, European, NR
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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