rs6855246
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
white matter volume measurement, cerebellar volume measurement
Primus SA et al. “Beyond volume: Unraveling the genetics of human brain geometry.” Science Advances 11(24):eadr1644 (2025)
Allele G
OR —
p 2.0e-43
N 19,862
Large GWAS
European
osteoarthritis
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.09
p 5.0e-29
N 400,167
Major Consortium StudyLarge GWAS
European
Arthralgia
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.06
p 4.0e-16
N 566,868
Major Consortium StudyLarge GWAS
multi-ancestry
intelligence
Davies G et al. “Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.” Nature Communications 9(1):2098 (2018)
Allele A
OR 7.68
p 2.0e-14
N 300,486
Large GWAS
European
Hill WD et al. “A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.” Molecular Psychiatry 24(2):169-181 (2019)
Allele A
OR 0.04
p 9.0e-13
N 248,482
Large GWAS
European
insomnia measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele G
OR 1.11
p 9.0e-14
N 1,331,010
Large GWAS
European
secreted frizzled-related protein 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.07
p 6.0e-12
N 47,745
Large GWAS
European
von Willebrand factor quality
Sabater-Lleal M et al. “Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.” Circulation 139(5):620-635 (2019)
Allele A
OR —
β 0.034
p 9.0e-10
N 46,354
Large GWAS
multi-ancestry
cerebral cortex area attribute
Grasby KL et al. “The genetic architecture of the human cerebral cortex.” Science (new York, N.y.) 367(6484) (2020)
Allele A
OR 2.44
p 5.0e-8
N 33,992
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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