rs6951286
This is a coding sequence variant variant in the BRI3 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
sex hormone-binding globulin measurement
Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele C
OR 2.43
p 8.0e-11
N 36,203
Major Consortium StudyLarge GWAS
European
low density lipoprotein cholesterol measurement
Kim YJ et al. “The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.” Nature Communications 13(1):6642 (2022)
Allele C
OR 0.02
p 2.0e-10
N 288,127
Large GWAS
East Asian
About BRI3
Enables identical protein binding activity. Predicted to be located in azurophil granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all BRI3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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