rs7020341
This is a intron variant variant in the ASTN2 gene.
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
dentate gyrus volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.07
p 1.0e-22
N 38,977
Large GWAS
European, East Asian
hippocampal CA4 volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.07
p 1.0e-22
N 38,977
Large GWAS
European, East Asian
hippocampal CA1 volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.06
p 5.0e-18
N 38,977
Large GWAS
European, East Asian
brain volume
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele C
OR 0.08
p 1.0e-15
N 21,282
Major Consortium StudyLarge GWAS
European
hippocampus molecular layer volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.05
p 8.0e-12
N 38,977
Large GWAS
European, East Asian
hippocampal CA3 volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.04
p 3.0e-9
N 38,977
Large GWAS
European, East Asian
amygdala volume
Ji Y et al. “Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes.” Nature Genetics 57(4):839-850 (2025)
Allele C
OR 0.05
p 4.0e-8
N 23,101
Large GWAS
multi-ancestry
hippocampal volume
Liu N et al. “Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes.” Nature Genetics 55(7):1126-1137 (2023)
Allele C
OR 0.06
p 1.0e-18
N 38,977
Large GWAS
European, East Asian
Klein M et al. “Genetic Markers of ADHD-Related Variations in Intracranial Volume.” The American Journal of Psychiatry 176(3):228-238 (2019)
Allele C
OR 6.70
p 2.0e-11
N 24,704
Large GWAS
European
About ASTN2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
View all ASTN2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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