rs7100709
This is a upstream gene variant variant in the AS3MT gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age at menopause
Zhang L et al. “Joint Genome-Wide Association Analyses Identified 49 Novel Loci For Age at Natural Menopause.” The Journal of Clinical Endocrinology and Metabolism 106(9):2574-2591 (2021)
Allele A
OR 0.10
p 2.0e-10
N 181,219
Large GWAS
European
About AS3MT
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]
View all AS3MT variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…