rs7114195
This variant is located in the TMPRSS5 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of transmembrane protease serine 5 in blood serum
Png G et al. “Mapping the serum proteome to neurological diseases using whole genome sequencing.” Nature Communications 12(1):7042 (2021)
Allele A
OR 0.77
p 2.0e-238
N 2,893
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
1 submitterAbout TMPRSS5
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
View all TMPRSS5 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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