rs7184597

This is a regulatory region variant variant in the RABEP2 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

IGF-1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.01

p 5.0e-13

N 394,642

Large GWAS

European

obesity

Berndt SI et al. “Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.” Nature Genetics 45(5):501-12 (2013)

Allele T

OR 1.10

p 7.0e-9

N 204,498

Meta-analysisLarge GWAS

European

About RABEP2

Predicted to enable GTPase activator activity and growth factor activity. Involved in regulation of cilium assembly. Located in Golgi apparatus; cytosol; and microtubule organizing center. [provided by Alliance of Genome Resources, Jul 2025]

View all RABEP2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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