rs7203216

This variant is located in the PHLPP2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glomerular filtration rate

Liu H et al. “Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.” Nature Genetics 54(7):950-962 (2022)

Allele T

OR 7.92

p 2.0e-15

N 1,508,659

Large GWAS

multi-ancestry

About PHLPP2

Predicted to enable metal ion binding activity and phosphoprotein phosphatase activity. Predicted to be involved in intracellular signal transduction. Located in several cellular components, including cilium; intercellular bridge; and mitotic spindle. [provided by Alliance of Genome Resources, Apr 2025]

View all PHLPP2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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