rs7212510
This is a upstream gene variant variant in the SARM1 gene.
▶GWAS Catalog Trait Associations (11)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (11)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
HERV-H LTR-associating protein 2 measurement
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.63
p 2.0e-26
N 466
Small GWAS
African American or Afro-Caribbean
level of E3 ISG15--protein ligase HERC5 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.51
p 1.0e-16
N 466
Small GWAS
African American or Afro-Caribbean
level of T-cell surface glycoprotein CD8 beta chain in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.51
p 1.0e-16
N 466
Small GWAS
African American or Afro-Caribbean
myocyte-specific enhancer factor 2C measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.10
p 3.0e-14
N 10,708
Large GWAS
European
level of protein LDOC1 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.46
p 2.0e-13
N 466
Small GWAS
African American or Afro-Caribbean
gastrin-releasing peptide measurement
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.44
p 2.0e-12
N 466
Small GWAS
African American or Afro-Caribbean
level of cleavage stimulation factor subunit 1 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.44
p 2.0e-12
N 466
Small GWAS
African American or Afro-Caribbean
protein SERAC1 measurement
Allele A
OR 0.17
p 3.0e-12
N 3,301
Large GWAS
European
level of prostaglandin E synthase 3 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.44
p 4.0e-12
N 466
Small GWAS
African American or Afro-Caribbean
level of homeobox protein Hox-C11 in blood serum
Surapaneni A et al. “Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.” Kidney International 102(5):1167-1177 (2022)
Allele A
OR 0.43
p 7.0e-12
N 466
Small GWAS
African American or Afro-Caribbean
About SARM1
Enables NAD+ nucleosidase activity; NAD+ nucleosidase activity, cyclic ADP-ribose generating; and identical protein binding activity. Involved in NAD catabolic process and response to axon injury. Is active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
View all SARM1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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