rs7247513
This is a regulatory region variant variant in the ZNF490 gene.
▶Research that mentions this SNP (1)
▶Propensity score‐based nonparametric test revealing genetic variants underlying bipolar disorderMethodsN=5,002Yuan Jiang et al.(2011)· Genetic Epidemiology
This methods paper presents a propensity score-based nonparametric test for genetic association that adjusts for covariates using genomic propensity scores. Applied to 1,998 bipolar disorder cases and 3,004 controls from the Wellcome Trust Case Control Consortium, the method identified three SNPs on chromosome 16 (rs2387823, rs1344485, rs11647459; p < 5×10⁻⁷) in strong linkage disequilibrium near RPGRIP1L that were missed by standard unadjusted methods, demonstrating that covariate-adjusted approaches can reveal genetic variants underlying bipolar disorder.
About ZNF490
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ZNF490 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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