ZNF490
zinc finger protein 490
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants30 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs7247513 | 19:12,691,185 | C/T | regulatory region variant | — |
| rs150047025 | 19:12,691,334 | C/T | — | uncertain significance |
| rs143593697 | 19:12,691,529 | C/T | — | uncertain significance |
| rs751310789 | 19:12,691,820 | T/A | — | uncertain significance |
| rs767270705 | 19:12,691,832 | C/T | — | uncertain significance |
| rs777221425 | 19:12,691,841 | G/C | — | uncertain significance |
| rs2022726105 | 19:12,691,891 | G/A | — | uncertain significance |
| rs770027002 | 19:12,691,921 | C/T | — | uncertain significance |
| rs762813141 | 19:12,691,925 | G/A | — | uncertain significance |
| rs2512752284 | 19:12,691,948 | G/T | — | uncertain significance |
| rs1365583148 | 19:12,692,053 | T/A | — | uncertain significance |
| rs771874028 | 19:12,692,089 | C/T | — | uncertain significance |
| rs1018756407 | 19:12,692,129 | C/G | — | uncertain significance |
| rs140140277 | 19:12,692,130 | C/G | — | uncertain significance |
| rs1395464819 | 19:12,692,284 | G/A | — | uncertain significance |
| rs59937497 | 19:12,692,289 | C/T | — | benign |
| rs758455628 | 19:12,692,336 | C/T | — | uncertain significance |
| rs187754525 | 19:12,692,476 | C/T | — | uncertain significance |
| rs757385492 | 19:12,692,501 | C/G | — | uncertain significance |
| rs372365655 | 19:12,692,531 | T/C | — | uncertain significance |
| rs922160388 | 19:12,694,274 | G/A | — | uncertain significance |
| rs2512754693 | 19:12,694,303 | C/T | — | uncertain significance |
| rs146197844 | 19:12,694,331 | G/C | — | uncertain significance |
| rs1488689097 | 19:12,694,358 | G/A | — | likely benign |
| rs750166712 | 19:12,694,360 | G/C | — | uncertain significance |
| rs185620637 | 19:12,703,542 | T/C | intron variant | — |
| rs56260719 | 19:12,716,985 | C/T | upstream gene variant | — |
| rs201522999 | 19:12,720,010 | T/A | — | uncertain significance |
| rs199661922 | 19:12,720,011 | C/A | — | uncertain significance |
| rs945957020 | 19:12,721,479 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.