Trait
SNPs associated with Male infertility
13 genetic variants across 6 genes have been associated with Male infertility in published research. Key genes include ENO4, FSHB, MTRR.
Associated variants13 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1801394 | MTRR | Increased male infertility risk in Asian populations | Meta-analysis |
| rs149265363 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs184686846 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs1043848039 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs185620637 | ZNF490 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs190342480 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs188613851 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs531148189 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs558556903 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs10835638 | FSHB | Increased male infertility risk | Large GWAS |
| rs1228269928 | NCKAP5 | GWAS association (p=3.0e-08) | Large GWAS |
| rs139862664 | ENO4 | GWAS association (p=3.0e-08) | Large GWAS |
| rs75957543 | UMODL1 | GWAS association (p=3.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.