rs72979233
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
prostate-associated microseminoprotein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.15
p 5.0e-22
N 10,708
Large GWAS
European
grip strength measurement
Willems SM et al. “Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.” Nature Communications 8:16015 (2017)
Allele A
OR 0.18
p 5.0e-13
N 142,035
Large GWAS
European
spine bone size
Styrkarsdottir U et al. “GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.” Nature Communications 10(1):2054 (2019)
Allele G
OR 0.05
p 2.0e-11
N 29,059
Large GWAS
multi-ancestry
osteoarthritis, knee
Kulm S et al. “Characterization of Genetic Risk of End-Stage Knee Osteoarthritis Treated with Total Knee Arthroplasty: A Genome-Wide Association Study.” The Journal of Bone and Joint Surgery. American Volume 104(20):1814-1820 (2022)
Allele G
OR 1.09
p 5.0e-10
N 389,548
Large GWAS
European
Henkel C et al. “Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacement.” Annals of the Rheumatic Diseases 82(3):384-392 (2023)
Allele G
OR 1.08
p 6.0e-10
N 661,143
Meta-analysisLarge GWAS
European
osteoarthritis, knee, total joint arthroplasty
Boer CG et al. “Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.” Cell 184(18):4784-4818.e17 (2021)
Allele A
OR 0.92
p 3.0e-9
N 252,041
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…