rs7395581

GWAS Catalog Trait Associations (17)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglycerides in small HDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 4.0e-26
N 136,016
Large GWAS
multi-ancestry

high density lipoprotein cholesterol measurement

Surakka I et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics 47(6):589-97 (2015)
Allele G
OR 0.06
p 2.0e-21
N 62,166
Large GWAS
European
Hoffmann TJ et al. A large electronic-health-record-based genome-wide study of serum lipids. Nature Genetics 50(3):401-413 (2018)
Allele G
OR
β 0.035
p 2.0e-17
N 94,674
Large GWAS
multi-ancestry

phospholipids in VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 2.0e-18
N 136,016
Large GWAS
multi-ancestry

triglycerides in small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 1.0e-17
N 136,016
Large GWAS
multi-ancestry

blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 2.0e-17
N 136,016
Large GWAS
multi-ancestry

apolipoprotein A 1 measurement, apolipoprotein B measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 3.0e-17
N 136,016
Large GWAS
multi-ancestry

total lipids in small VLDL

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.03
p 3.0e-17
N 136,016
Large GWAS
multi-ancestry

triglyceride measurement, phospholipid level

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 3.0e-17
N 136,016
Large GWAS
multi-ancestry

free cholesterol in small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.03
p 2.0e-15
N 136,016
Large GWAS
multi-ancestry

triglycerides in very small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.03
p 2.0e-15
N 136,016
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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