rs739846

This is a intron variant variant in the SUGP1 gene.

GWAS Catalog Trait Associations (29)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cathepsin Z measurement

Allele A
OR 0.14
p 5.0e-51
N 47,745
Large GWAS
European

cirrhosis of liver

Allele A
OR 0.30
p 3.0e-47
N 1,580,011
Large GWAS
European

tyrosine measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 3.0e-19
N 450,015
Large GWAS
multi-ancestry

hematocrit

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.04
p 3.0e-18
N 407,836
Major Consortium StudyLarge GWAS
European

level of fucose mutarotase in blood

Allele A
OR 0.09
p 1.0e-17
N 47,745
Large GWAS
European

formimidoyltransferase-cyclodeaminase measurement

Allele A
OR 0.09
p 9.0e-16
N 47,745
Large GWAS
European

level of metal cation symporter ZIP14 in blood

Allele A
OR 0.08
p 2.0e-14
N 47,745
Large GWAS
European

glutathione S-transferase A1 measurement

Allele A
OR 0.07
p 6.0e-14
N 47,745
Large GWAS
European

diabetic eye disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.11
p 1.0e-13
N 431,357
Major Consortium StudyLarge GWAS
European

About SUGP1

SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]

View all SUGP1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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