Trait
SNPs associated with Diabetic Eye Disease
61 genetic variants across 22 genes have been associated with Diabetic Eye Disease in published research. Key genes include ADCY5, APOE, C5orf67.
Associated variants61 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs34872471 | TCF7L2 | GWAS association (p=2.0e-248) | Major Consortium Study |
| rs1421085 | FTO | GWAS association (p=3.0e-70) | Major Consortium Study |
| rs1558902 | FTO | GWAS association (p=2.0e-50) | Major Consortium Study |
| rs10811661 | — | GWAS association (p=4.0e-42) | Major Consortium Study |
| rs1794269 | — | GWAS association (p=1.0e-38) | Major Consortium Study |
| rs10811660 | — | GWAS association (p=9.0e-35) | Major Consortium Study |
| rs11187143 | — | GWAS association (p=1.0e-28) | Major Consortium Study |
| rs13266634 | SLC30A8 | GWAS association (p=1.0e-27) | Major Consortium Study |
| rs3802177 | SLC30A8 | GWAS association (p=4.0e-27) | Major Consortium Study |
| rs9348441 | CDKAL1 | GWAS association (p=4.0e-27) | Major Consortium Study |
| rs234864 | — | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs3998159 | — | GWAS association (p=3.0e-25) | Major Consortium Study |
| rs9457 | WFS1 | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs13389219 | COBLL1 | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs2972156 | — | GWAS association (p=6.0e-22) | Major Consortium Study |
| rs1635852 | JAZF1 | GWAS association (p=3.0e-21) | Major Consortium Study |
| rs77791126 | THADA | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs849133 | — | GWAS association (p=5.0e-20) | Major Consortium Study |
| rs3747207 | PNPLA3 | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs738408 | PNPLA3 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs76160968 | — | GWAS association (p=6.0e-18) | Major Consortium Study |
| rs1565756 | HMG20A | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs71304101 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
| rs76895963 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
| rs1215468 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs4737000 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs6777684 | LOC107986166 | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs10852123 | — | GWAS association (p=7.0e-15) | Major Consortium Study |
| rs75432112 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs11257655 | — | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs2796441 | TLE1-DT | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs11688682 | — | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs1346 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs243083 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs739846 | SUGP1 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs11708067 | ADCY5 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs61779313 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs12641981 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs4929965 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs10842987 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs7156625 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs7647481 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs703973 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs17265513 | ZHX3 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs59360790 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs4696136 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs1815311 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs7801117 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs3808454 | TRPS1 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs72999033 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=6.0e-259) | Major Consortium Study |
| rs11466334 | TGFB1 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs2237897 | KCNQ1 | GWAS association (p=4.0e-34) | Major Consortium Study |
| rs3918298 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs459193 | C5orf67 | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs9859406 | — | GWAS association (p=2.0e-43) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs376993806 | GPSM1 | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs11759026 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs3095447 | — | GWAS association (p=3.0e-08) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.