rs74156086

This variant is located in the ZNF365 gene.

ClinVar annotation

Likely Benign☆☆☆
1 submitter1 publication
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About ZNF365

This gene encodes a zinc finger protein that may play a role in the repair of DNA damage and maintenance of genome stability. The N-terminal C2H2 zinc finger motif is required to form a protein complex with PARP1 and MRE11, which are known to be involved in the restart of stalled DNA replication forks. A mutation in this gene may be associated with breast cancer susceptibility. [provided by RefSeq, Mar 2020]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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