rs742396
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
brain volume
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele G
OR 0.07
p 2.0e-12
N 21,282
Major Consortium StudyLarge GWAS
European
white matter integrity
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele G
OR 0.07
p 9.0e-11
N 20,860
Major Consortium StudyLarge GWAS
European
brain age measurement
Zhao X et al. “Regulatory Genomic Circuitry of Brain Age by Integrative Functional Genomic Analyses.” Genomics, Proteomics & Bioinformatics 23(5) (2025)
Allele C
OR 0.14
p 3.0e-9
N 35,702
Large GWAS
European
amount of iron in brain
Casanova F et al. “MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort.” Neurobiology of Disease 197:106539 (2024)
Allele C
OR 0.04
p 6.0e-9
N 39,533
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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