rs74587733
This variant is located in the CD14 gene.
▶ClinVar annotation
Benign★☆☆☆
1 submitter1 publicationAbout CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
View all CD14 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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