rs746839

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

mathematical ability

Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele C
OR 0.01
p 1.0e-17
N 811,539
Large GWAS
European

biological sex

Pirastu N et al. “Genetic analyses identify widespread sex-differential participation bias.” Nature Genetics 53(5):663-671 (2021)
Allele G
OR 0.01
p 3.0e-13
N 2,462,132
Large GWAS
European

wellbeing measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele G
OR 0.01
p 6.0e-9
N 410,603
Large GWAS
European
Baselmans BML et al. “A genetic perspective on the relationship between eudaimonic -and hedonic well-being.” Scientific Reports 8(1):14610 (2018)
Allele G
OR 0.02
p 1.0e-8
N 221,575
Large GWAS
European

C-reactive protein measurement

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.01
p 2.0e-8
N 436,491
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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