rs74685739

This variant is located in the LRP1B gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

vaginal microbiome measurement

Fan W et al. “Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.” Msystems 6(4):e0015821 (2021)

Allele A

OR 1.34

p 1.0e-8

N 315

Small GWAS

East Asian

About LRP1B

This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]

View all LRP1B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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