rs748670681
This variant is located in the TNRC18 gene.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
psoriasis
Heikkilä A et al. “Genetic Study of Psoriasis Highlights its Close Link with Socioeconomic Status and Affective Symptoms.” The Journal of Investigative Dermatology 144(12):2719-2729 (2024)
Allele T
OR 1.38
p 3.0e-20
N 925,649
Large GWAS
multi-ancestry
ulcerative colitis
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.73
p 2.0e-16
N 596,621
Large GWAS
multi-ancestry
Graves disease
White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)
Allele T
OR 0.60
p 4.0e-16
N 1,881,665
Large GWAS
European
iritis
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.71
p 5.0e-15
N 656,395
Large GWAS
multi-ancestry
uveitis
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.71
p 5.0e-15
N 655,467
Large GWAS
multi-ancestry
About TNRC18
Predicted to enable chromatin binding activity. Located in cytosol; mitochondrion; and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all TNRC18 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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