rs7546668
This is a upstream gene variant variant in the DNAJC16 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
kidney cancer
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.12
p 6.0e-12
N 630,800
Major Consortium StudyLarge GWAS
multi-ancestry
gout
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.05
p 1.0e-11
N 440,023
Major Consortium StudyLarge GWAS
European
serum creatinine amount, glomerular filtration rate
Gorski M et al. “1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.” Scientific Reports 7:45040 (2017)
Allele C
OR 0.01
p 1.0e-9
N 110,517
Meta-analysisLarge GWAS
European
About DNAJC16
Involved in regulation of autophagosome size. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all DNAJC16 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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