rs757158
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
free cholesterol to total lipids in large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 2.0e-14
N 450,015
Large GWAS
multi-ancestry
cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 4.0e-12
N 450,015
Large GWAS
multi-ancestry
aspartate aminotransferase, cytoplasmic measurement
Suhre K et al. “Connecting genetic risk to disease end points through the human blood plasma proteome.” Nature Communications 8:14357 (2017)
Allele T
OR 0.31
p 7.0e-12
N 997
Small GWAS
multi-ancestry
triglycerides to total lipids in chylomicrons and extremely large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 5.0e-11
N 450,015
Large GWAS
multi-ancestry
paraoxonase-1 measurement
Caron B et al. “Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.” Genome Medicine 14(1):28 (2022)
Allele C
OR 0.09
p 5.0e-9
N 400
Small GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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