rs75772222
This is a intron variant variant in the STXBP6 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
corneal topography
Fan Q et al. “Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error.” Communications Biology 3(1):133 (2020)
Allele T
OR —
β 0.020
p 1.0e-37
N 44,042
Meta-analysisLarge GWAS
multi-ancestry
About STXBP6
Enables cadherin binding activity involved in cell-cell adhesion. Predicted to be involved in negative regulation of exocytosis. Located in adherens junction. [provided by Alliance of Genome Resources, Jul 2025]
View all STXBP6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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