Trait
SNPs associated with Corneal Topography
77 genetic variants across 31 genes have been associated with Corneal Topography in published research. Key genes include ADAMTS6, ADAMTS7, ARID5B.
Associated variants77 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12702376 | — | GWAS association (p=3.0e-86) | Meta-analysis |
| rs1800813 | PDGFRA | GWAS association (p=2.0e-73) | Meta-analysis |
| rs2630445a | — | GWAS association (p=5.0e-67) | Meta-analysis |
| rs807037 | — | GWAS association (p=7.0e-54) | Meta-analysis |
| rs1548942 | — | GWAS association (p=5.0e-50) | Meta-analysis |
| rs2245601 | CHRND | GWAS association (p=1.0e-48) | Meta-analysis |
| rs7959830 | — | GWAS association (p=9.0e-47) | Meta-analysis |
| rs3737611 | MTOR | GWAS association (p=1.0e-46) | Meta-analysis |
| rs7708378a | — | GWAS association (p=6.0e-45) | Meta-analysis |
| rs166976 | — | GWAS association (p=4.0e-44) | Meta-analysis |
| rs13050142 | — | GWAS association (p=2.0e-40) | Meta-analysis |
| rs6064518 | — | GWAS association (p=7.0e-40) | Meta-analysis |
| rs7657200 | — | GWAS association (p=2.0e-38) | Meta-analysis |
| rs4887113 | ADAMTS7 | GWAS association (p=6.0e-38) | Meta-analysis |
| rs7004112 | — | GWAS association (p=6.0e-38) | Meta-analysis |
| rs75772222 | STXBP6 | GWAS association (p=1.0e-37) | Meta-analysis |
| rs9366426 | — | GWAS association (p=5.0e-37) | Meta-analysis |
| rs7948458 | — | GWAS association (p=2.0e-36) | Meta-analysis |
| rs67612840 | OFCC1 | GWAS association (p=4.0e-35) | Meta-analysis |
| rs3132309 | — | GWAS association (p=7.0e-35) | Meta-analysis |
| rs7327381 | — | GWAS association (p=4.0e-34) | Meta-analysis |
| rs16896276 | LCORL | GWAS association (p=1.0e-31) | Meta-analysis |
| rs961755 | LOC105377956 | GWAS association (p=1.0e-30) | Meta-analysis |
| rs11740254 | — | GWAS association (p=5.0e-30) | Meta-analysis |
| rs485554 | — | GWAS association (p=2.0e-27) | Meta-analysis |
| rs4083463 | — | GWAS association (p=3.0e-24) | Meta-analysis |
| rs4837104 | — | GWAS association (p=3.0e-24) | Meta-analysis |
| rs11181913 | — | GWAS association (p=1.0e-22) | Meta-analysis |
| rs13180294 | — | GWAS association (p=2.0e-22) | Meta-analysis |
| rs9316971 | — | GWAS association (p=4.0e-21) | Meta-analysis |
| rs4620141 | — | GWAS association (p=2.0e-20) | Meta-analysis |
| rs10786330 | — | GWAS association (p=2.0e-19) | Meta-analysis |
| rs6831679 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs60078183a | — | GWAS association (p=4.0e-16) | Meta-analysis |
| rs11204213 | RBP3 | GWAS association (p=1.0e-13) | Meta-analysis |
| rs9506725 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs2630445 | — | GWAS association (p=4.0e-12) | Meta-analysis |
| rs184926585 | MAPRE2 | GWAS association (p=5.0e-11) | Meta-analysis |
| rs11211514 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs9806595 | FBN1 | GWAS association (p=6.0e-09) | Meta-analysis |
| rs9506725a | — | GWAS association (p=1.0e-78) | Meta-analysis |
| rs945170 | — | GWAS association (p=3.0e-30) | Meta-analysis |
| rs11204213a | — | GWAS association (p=4.0e-13) | Meta-analysis |
| rs4074961 | RSPO1 | GWAS association (p=7.0e-100) | Meta-analysis |
| rs10663094 | — | GWAS association (p=1.0e-30) | Meta-analysis |
| rs9938149 | ZNF469 | GWAS association (p=2.0e-49) | Large GWAS |
| rs10453441 | WNT7B | GWAS association (p=3.0e-40) | Large GWAS |
| rs1536482 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs930847 | LRRK1 | GWAS association (p=6.0e-19) | Large GWAS |
| rs74225573 | MTOR | GWAS association (p=6.0e-18) | Large GWAS |
| rs2721051 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs17084051 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs17036350 | MTOR | GWAS association (p=4.0e-13) | Large GWAS |
| rs6496932 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs1538138 | LINC02542 | GWAS association (p=1.0e-12) | Large GWAS |
| rs17103186 | LINC01389 | GWAS association (p=3.0e-12) | Large GWAS |
| rs4894535 | FNDC3B | GWAS association (p=5.0e-12) | Large GWAS |
| rs1007000 | LPAR1 | GWAS association (p=5.0e-12) | Large GWAS |
| rs7044529 | COL5A1 | GWAS association (p=5.0e-12) | Large GWAS |
| rs11145951 | — | GWAS association (p=6.0e-12) | Large GWAS |
| rs96067 | COL8A2 | GWAS association (p=3.0e-11) | Large GWAS |
| rs785422 | TJP1 | GWAS association (p=3.0e-11) | Large GWAS |
| rs2307121 | ADAMTS6 | GWAS association (p=6.0e-11) | Large GWAS |
| rs1564892 | GLT8D2 | GWAS association (p=2.0e-10) | Large GWAS |
| rs4718428 | TMEM248 | GWAS association (p=3.0e-10) | Large GWAS |
| rs12913547 | SMAD3 | GWAS association (p=5.0e-10) | Large GWAS |
| rs7090871 | ARID5B | GWAS association (p=6.0e-10) | Large GWAS |
| rs12940030 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs2114039 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs7606754 | COL4A3 | GWAS association (p=1.0e-09) | Large GWAS |
| rs752092 | CHSY1 | GWAS association (p=2.0e-09) | Large GWAS |
| rs11763147 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs4938174 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs1034200 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs1324183 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs7620503 | LINC00578 | GWAS association (p=1.0e-08) | Large GWAS |
| rs3931397 | NR3C2 | GWAS association (p=4.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.