rs757978

This is a protein-altering variant in the FARP2 gene.

Research that mentions this SNP (1)

Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy
AssociationN=1,711Savage DA et al.(2008)· Diabetologia

This case-control study investigated 1,111 non-synonymous SNPs in 1,711 type 1 diabetic individuals (894 cases with diabetic nephropathy, 817 controls) to assess genetic susceptibility to diabetic nephropathy. After correction for multiple testing, no SNPs demonstrated significant associations with diabetic nephropathy, including in subgroup analyses by ESRD status or diabetes duration.

Traits studied:Diabetic nephropathyEnd-stage renal disease (ESRD)

About FARP2

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within Rac protein signal transduction and neuron remodeling. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all FARP2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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