FARP2

FERM, ARH/RhoGEF and pleckstrin domain protein 2

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within Rac protein signal transduction and neuron remodeling. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants129 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs3755397	2:242,294,913	A/G	regulatory region variant	—
rs1476698	2:242,296,449	A/T	—	—
rs60624480	2:242,297,118	G/T	—	—
rs139981990	2:242,312,543	A/C	—	likely benign
rs375264796	2:242,312,571	C/T	—	uncertain significance
rs149811606	2:242,312,574	T/G	—	uncertain significance
rs542172960	2:242,312,593	T/C	—	likely benign
rs372859965	2:242,312,602	G/A	—	uncertain significance
rs147738223	2:242,312,617	G/A	—	conflicting classifications of pathogenicity
rs61739735	2:242,312,655	C/T	—	likely benign
rs150312458	2:242,312,656	A/G	—	benign
rs12695001	2:242,342,984	T/A	—	—
rs141878745	2:242,343,297	G/A	—	likely benign
rs1429475083	2:242,343,310	A/G	—	uncertain significance
rs200802062	2:242,343,336	C/G	—	likely benign
rs2549474289	2:242,343,345	T/A	—	uncertain significance
rs2240479	2:242,350,466	A/G	synonymous variant	—
rs145651106	2:242,352,717	C/G	—	benign
rs138549813	2:242,352,747	G/A	—	likely benign
rs760103920	2:242,352,755	G/A	—	uncertain significance
rs185331144	2:242,352,775	G/A	—	uncertain significance
rs148530431	2:242,352,785	C/T	—	uncertain significance
rs144620628	2:242,357,510	G/A	—	uncertain significance
rs757978	2:242,371,101	C/T	missense variant	—
rs765404341	2:242,371,110	A/G	—	uncertain significance
rs185323681	2:242,371,116	T/C	—	likely benign
rs768773220	2:242,373,607	G/A	—	uncertain significance
rs753632692	2:242,373,610	G/C	—	uncertain significance
rs2549516870	2:242,373,627	A/C	—	uncertain significance
rs749572946	2:242,373,718	G/A	—	uncertain significance
rs1178898578	2:242,374,414	G/A	—	uncertain significance
rs145392931	2:242,374,453	C/T	—	likely benign
rs749056821	2:242,375,906	A/G	—	uncertain significance
rs376886611	2:242,375,912	C/G	—	uncertain significance
rs372605073	2:242,375,921	G/A	—	likely benign
rs140902248	2:242,375,925	G/A	—	uncertain significance
rs764253084	2:242,375,941	C/G	—	uncertain significance
rs751846420	2:242,375,952	A/G	—	uncertain significance
rs971097956	2:242,380,794	T/G	—	uncertain significance
rs767029835	2:242,380,896	A/G	—	uncertain significance
rs200063144	2:242,380,917	C/A	—	likely benign
rs562576527	2:242,380,938	C/G	—	uncertain significance
rs757599494	2:242,380,953	G/A	—	uncertain significance
rs114094334	2:242,380,976	C/T	—	benign
rs3771570	2:242,382,864	C/T	regulatory region variant	—
rs76825718	2:242,392,854	G/T	—	—
rs187443429	2:242,392,862	C/T	intron variant	—
rs2302010	2:242,394,142	G/A	intron variant	—
rs143766466	2:242,396,192	C/T	—	uncertain significance
rs189584342	2:242,396,200	C/T	—	uncertain significance
rs145630778	2:242,396,209	C/A	—	uncertain significance
rs150929124	2:242,396,235	G/C	—	uncertain significance
rs1228457044	2:242,396,243	T/C	—	uncertain significance
rs141474478	2:242,396,308	G/C	—	likely benign
rs376390945	2:242,396,319	C/T	—	likely benign
rs1485513218	2:242,396,331	A/C	—	uncertain significance
rs886815	2:242,396,426	G/A	intron variant	—
rs757974	2:242,399,927	G/A	intron variant	—
rs201060373	2:242,401,939	G/A	—	uncertain significance
rs141826550	2:242,401,941	G/A	—	likely benign
rs756759668	2:242,401,945	C/T	—	uncertain significance
rs777894186	2:242,401,983	G/A	—	uncertain significance
rs2064052167	2:242,401,993	G/A	—	uncertain significance
rs139008133	2:242,402,016	G/A	—	benign
rs200603089	2:242,402,020	T/C	—	uncertain significance
rs149617362	2:242,402,025	G/A	—	uncertain significance
rs145231241	2:242,402,806	G/C	—	likely benign
rs138838419	2:242,402,857	C/T	—	likely benign
rs762295762	2:242,403,308	A/T	—	likely benign
rs2549555359	2:242,403,317	A/T	—	uncertain significance
rs1228359982	2:242,403,334	A/C	—	uncertain significance
rs772510982	2:242,403,382	T/C	—	uncertain significance
rs775908482	2:242,407,580	A/G	—	uncertain significance
rs200102806	2:242,407,618	C/T	—	uncertain significance
rs371446032	2:242,407,619	G/T	—	uncertain significance
rs754554546	2:242,407,624	A/G	—	uncertain significance
rs2064224358	2:242,407,648	G/A	—	uncertain significance
rs2064224764	2:242,407,669	T/A	—	uncertain significance
rs373829392	2:242,407,688	C/T	—	uncertain significance
rs374552131	2:242,407,727	G/A	—	uncertain significance
rs368744784	2:242,407,738	C/T	—	uncertain significance
rs151203664	2:242,407,739	G/A	—	uncertain significance
rs140462275	2:242,407,748	G/A	—	uncertain significance
rs776438616	2:242,407,763	C/T	—	likely benign
rs754367363	2:242,407,790	A/T	—	uncertain significance
rs61740951	2:242,415,325	C/T	—	benign
rs1445535652	2:242,415,364	G/T	—	uncertain significance
rs1337955553	2:242,415,376	A/G	—	likely benign
rs763420846	2:242,415,392	C/T	—	uncertain significance
rs144542827	2:242,422,890	G/A	—	uncertain significance
rs766357961	2:242,422,910	C/G	—	uncertain significance
rs752656317	2:242,423,667	T/C	—	uncertain significance
rs765390864	2:242,423,704	C/G	—	uncertain significance
rs200700734	2:242,423,711	C/T	—	uncertain significance
rs140628478	2:242,423,712	G/A	—	uncertain significance
rs938331976	2:242,428,024	C/T	—	—
rs62000396	2:242,429,427	C/T	—	benign
rs1574916267	2:242,429,445	C/T	—	likely benign
rs773098796	2:242,429,446	G/A	—	uncertain significance
rs143557762	2:242,430,480	C/T	—	uncertain significance

Showing 100 of 129 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.