Trait
SNPs associated with Chronic lymphocytic leukemia
84 genetic variants across 30 genes have been associated with Chronic lymphocytic leukemia in published research. Key genes include ACOXL, ACTA2, BAK1.
Associated variants84 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs35923643 | GRAMD1B | GWAS association (p=4.0e-58) | Meta-analysis |
| rs391855 | — | GWAS association (p=1.0e-28) | Meta-analysis |
| rs58055674 | — | GWAS association (p=2.0e-27) | Meta-analysis |
| rs9391997 | — | GWAS association (p=9.0e-22) | Meta-analysis |
| rs8024033 | — | GWAS association (p=7.0e-19) | Meta-analysis |
| rs2052702 | — | GWAS association (p=4.0e-18) | Meta-analysis |
| rs2953196 | — | GWAS association (p=5.0e-16) | Meta-analysis |
| rs9270750 | — | GWAS association (p=6.0e-16) | Meta-analysis |
| rs4406737 | FAS | GWAS association (p=1.0e-14) | Meta-analysis |
| rs72742684 | LOC105370832 | GWAS association (p=2.0e-13) | Meta-analysis |
| rs140099016 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs9308731 | BCL2L11 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs9880772 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs4987856 | — | GWAS association (p=4.0e-11) | Meta-analysis |
| rs1359742 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs73718779 | SERPINB6 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs13015798 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs2521269 | C11orf21 | GWAS association (p=4.0e-08) | Meta-analysis |
| rs9815073 | LPP | GWAS association (p=4.0e-08) | Meta-analysis |
| rs735665 | GRAMD1B | GWAS association (p=4.0e-39) | Large GWAS |
| rs34004493 | SP140 | GWAS association (p=4.0e-32) | Large GWAS |
| rs11637565 | — | GWAS association (p=2.0e-31) | Large GWAS |
| rs9392504 | — | GWAS association (p=1.0e-28) | Large GWAS |
| rs13397985 | SP110 | GWAS association (p=1.0e-22) | Large GWAS |
| rs872071 | IRF4 | GWAS association (p=2.0e-20) | Large GWAS |
| rs9271176 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs142239370 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs13401811 | ACOXL | GWAS association (p=2.0e-18) | Large GWAS |
| rs142215530 | LOC105370832 | GWAS association (p=2.0e-18) | Large GWAS |
| rs11187157 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs7176508 | — | GWAS association (p=8.0e-18) | Large GWAS |
| rs17483466 | ACOXL | GWAS association (p=4.0e-17) | Large GWAS |
| rs391023 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs210143 | BAK1 | GWAS association (p=6.0e-16) | Large GWAS |
| rs2466029 | CASC19 | GWAS association (p=7.0e-16) | Large GWAS |
| rs210142 | BAK1 | GWAS association (p=9.0e-16) | Large GWAS |
| rs6586163 | ACTA2 | GWAS association (p=1.0e-15) | Large GWAS |
| rs1439287 | ACOXL | GWAS association (p=5.0e-15) | Large GWAS |
| rs11636802 | LOC105370832 | GWAS association (p=2.0e-13) | Large GWAS |
| rs34676223 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs4987855 | BCL2 | GWAS association (p=3.0e-12) | Large GWAS |
| rs3755397 | FARP2 | GWAS association (p=9.0e-12) | Large GWAS |
| rs77551289 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs61904987 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs7558911 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs2651823 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs71597109 | BANK1 | GWAS association (p=1.0e-10) | Large GWAS |
| rs41271473 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs9273363 | HLA-DQB1 | Increased risk of chronic lymphocytic leukemia | Large GWAS |
| rs7944004 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs2236256 | OPRM1 | GWAS association (p=2.0e-10) | Large GWAS |
| rs1849913 | LPP | GWAS association (p=3.0e-10) | Large GWAS |
| rs898518 | LEF1 | GWAS association (p=4.0e-10) | Large GWAS |
| rs7705526 | TERT | GWAS association (p=6.0e-10) | Large GWAS |
| rs1476569 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs1044873 | IRF8 | GWAS association (p=1.0e-09) | Large GWAS |
| rs10936599 | MYNN | GWAS association (p=2.0e-09) | Large GWAS |
| rs3769825 | CASP8 | GWAS association (p=3.0e-09) | Large GWAS |
| rs6858698 | CAMK2D | GWAS association (p=3.0e-09) | Large GWAS |
| rs140522 | ODF3B | GWAS association (p=3.0e-09) | Large GWAS |
| rs11083846 | PRKD2 | GWAS association (p=4.0e-09) | Large GWAS |
| rs7690934 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs388368 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs2267708 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs1679013 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6561593 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs2466035 | CASC19 | GWAS association (p=2.0e-08) | Large GWAS |
| rs1800682 | ACTA2 | GWAS association (p=2.0e-08) | Large GWAS |
| rs3800461 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs7133288 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs4368253 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs17246404 | POT1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs874460 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1036935 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs72098212 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs12971302 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs926070 | TSBP1-AS1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs57214277 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs4869818 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs2511714 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs888096 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs6489882 | OAS3 | GWAS association (p=5.0e-08) | Large GWAS |
| rs7254272 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs674313 | — | GWAS association (p=7.0e-09) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.