Trait
SNPs associated with GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
13 genetic variants across 7 genes have been associated with GRN-related frontotemporal lobar degeneration with Tdp43 inclusions in published research. Key genes include FARP2, GRN, LRP1B.
Associated variants13 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12973192 | UNC13A | GWAS association (p=9.0e-10) | Large GWAS |
| rs5848 | GRN | GWAS association (p=6.0e-09) | Large GWAS |
| rs540663062 | TRPC4 | GWAS association (p=7.0e-09) | Large GWAS |
| rs117642163 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs35902922 | LRP1B | GWAS association (p=1.0e-08) | Large GWAS |
| rs76742217 | RCL1 | GWAS association (p=2.0e-08) | Large GWAS |
| rs576561313 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs138698596 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs138959102 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs886815 | FARP2 | GWAS association (p=4.0e-08) | Large GWAS |
| rs527749954 | PDS5B | GWAS association (p=4.0e-08) | Large GWAS |
| rs146589681 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs871269 | — | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.