rs35902922
This is a intron variant variant in the LRP1B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
Pottier C et al. “Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.” Nature Communications 16(1):3914 (2025)
Allele C
OR 11.86
p 1.0e-8
N 3,620
Large GWAS
European
About LRP1B
This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]
View all LRP1B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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