rs76122535
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
white matter integrity, age at assessment
Traylor M et al. “The BS variant of C4 protects against age-related loss of white matter microstructural integrity.” Brain : a Journal of Neurology 145(1):295-304 (2022)
Allele G
OR —
p 4.0e-12
N 31,125
Large GWAS
European
white matter integrity
Persyn E et al. “Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.” Nature Communications 11(1):2175 (2020)
Allele G
OR 0.36
p 6.0e-9
N 17,663
Large GWAS
European
gut microbiome measurement, breastfeeding duration
Stickley SA et al. “Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.” The Journal of Allergy and Clinical Immunology 156(2):433-448 (2025)
Allele G
OR —
β 0.020
p 1.0e-8
N 688
Small GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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