rs76130087
This variant is located in the ARHGEF26 gene.
▶ClinVar annotation
About ARHGEF26
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
View all ARHGEF26 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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