rs7616215

This variant is located in the LOC105377067 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Behcet's syndrome

Kirino Y et al. “Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.” Nature Genetics 45(2):202-7 (2013)
Allele C
OR 1.39
p 4.0e-13
N 2,493
Large GWAS
multi-ancestry

celiac disease

Trynka G et al. “Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.” Nature Genetics 43(12):1193-201 (2011)
Allele C
OR 1.12
p 9.0e-9
N 24,269
Large GWAS
multi-ancestry
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Research that mentions this SNP (1)

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Two-stage association study in Chinese Han identifies two independent associations in CCR1/CCR3 locus as candidate for Behçet’s disease susceptibility
AssociationN=2,338Shengping Hou et al.(2012)· Human Genetics

A two-stage association study in Chinese Han population identified multiple independent SNPs in the CCR1/CCR3 locus associated with Behçet's disease susceptibility. Three SNPs (rs13084057, rs13092160, rs13075270) showed consistent association across both stages with combined P-values ranging from 2.76×10⁻⁷ to 6.50×10⁻⁸ and odds ratios of 0.28-0.32, indicating protective effects. SNP rs13092160 was identified as an eQTL variant affecting CCR1 and CCR3 gene expression.

Traits studied:Behçet's disease
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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