rs763774150

This variant is located in the TLE1 gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About TLE1

Enables DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Jul 2025]

View all TLE1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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