rs76473275

This is a intron variant variant in the SDCCAG8 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

health study participation

Tyrrell J et al. “Genetic predictors of participation in optional components of UK Biobank.” Nature Communications 12(1):886 (2021)

Allele T

OR 0.88

p 3.0e-12

N 300,639

Major Consortium StudyLarge GWAS

European

hypothyroidism

White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)

Allele C

OR 0.03

p 3.0e-9

N 1,786,062

Large GWAS

European

About SDCCAG8

This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]

View all SDCCAG8 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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