rs772089801

This variant is located in the FCRL4 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About FCRL4

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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