rs772267698
This variant is located in the SFRP1 gene.
▶ClinVar annotation
About SFRP1
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
View all SFRP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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