rs77273581
This variant is located in the TNFSF13B gene.
▶ClinVar annotation
Benign★★★☆
2 submitters2 publicationsAbout TNFSF13B
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
View all TNFSF13B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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