rs774363859

This variant is located in the IRF7 gene.

ClinVar annotation

Likely Benign☆☆☆
1 submitter1 publication

Immunodeficiency 39

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About IRF7

This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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