rs7744020

This is a downstream gene variant variant in the HLA-DQB1-AS1 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

allergic rhinitis

Johansson Å et al. “Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.” Human Molecular Genetics 28(23):4022-4041 (2019)

Allele A

OR 1.13

p 4.0e-25

N 258,688

Major Consortium StudyLarge GWAS

European

seasonal allergic rhinitis

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.08

p 1.0e-17

N 394,626

Large GWAS

European

narcolepsy-cataplexy syndrome, age at onset

Han F et al. “Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.” Plos Genetics 9(10):e1003880 (2013)

Allele A

OR 1.90

p 8.0e-9

N 1,000

Large GWAS

East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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